Validation of CT-based ventilation and perfusion biomarkers with histopathology confirms radiation-induced pulmonary changes in a porcine model

Abstract Imaging biomarkers can assess disease progression or prognoses and are valuable tools to help guide interventions. Particularly in lung imaging, biomarkers present an opportunity to extract regional information that is more robust to the patient’s condition prior to intervention than curren...

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Bibliographic Details
Main Authors: Mattison J. Flakus, Antonia E. Wuschner, Eric M. Wallat, Melissa Graham, Wei Shao, Dhanansayan Shanmuganayagam, Gary E. Christensen, Joseph M. Reinhardt, John E. Bayouth
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36292-0