Conditional RNA interference in mammalian cells via RNA transactivation
Abstract RNA interference (RNAi) is a powerful tool for sequence-specific gene knockdown in therapeutic and research applications. However, spatiotemporal control of RNAi is required to decrease nonspecific targeting, potential toxicity, and allow targeting of essential genes. Herein we describe a c...
| Hlavní autoři: | , , , , , |
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| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Nature Portfolio
2024-08-01
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| Edice: | Nature Communications |
| On-line přístup: | https://doi.org/10.1038/s41467-024-50600-w |