Conditional RNA interference in mammalian cells via RNA transactivation

Conditional RNA interference in mammalian cells via RNA transactivation

Abstract RNA interference (RNAi) is a powerful tool for sequence-specific gene knockdown in therapeutic and research applications. However, spatiotemporal control of RNAi is required to decrease nonspecific targeting, potential toxicity, and allow targeting of essential genes. Herein we describe a c...

Full description

Bibliographic Details
Main Authors: Yu Zhou, Peike Sheng, Jiayi Li, Yudan Li, Mingyi Xie, Alexander A. Green
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-50600-w

Internet

https://doi.org/10.1038/s41467-024-50600-w

Similar Items