Conditional RNA interference in mammalian cells via RNA transactivation
Abstract RNA interference (RNAi) is a powerful tool for sequence-specific gene knockdown in therapeutic and research applications. However, spatiotemporal control of RNAi is required to decrease nonspecific targeting, potential toxicity, and allow targeting of essential genes. Herein we describe a c...
| Main Authors: | , , , , , |
|---|---|
| 格式: | 文件 |
| 语言: | English |
| 出版: |
Nature Portfolio
2024-08-01
|
| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/s41467-024-50600-w |