Development of multi-drug resistance to anticancer drugs in HepG2 cells due to MRP2 upregulation on exposure to menthol.

<h4>Background</h4>Menthol exerts relaxing, antibacterial, and anti-inflammatory activities, and is marketed as a functional food and therapeutic drug.<h4>Aim</h4>In the present study, the effects of menthol on the expression of multidrug resistance associated protein 2 (MRP2...

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Bibliographic Details
Main Authors: Katsuhito Nagai, Mayuko Tamura, Ryuga Murayama, Shuhei Fukuno, Takuya Ito, Hiroki Konishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0291822