Dsg3 epitope-specific signalling in pemphigus

Dsg3 epitope-specific signalling in pemphigus

IntroductionPemphigus is an autoantibody driven disease that impairs the barrier function of the skin and mucosa by disrupting desmosomes and thereby impeding cellular cohesion. It is known that the different clinical phenotypes of pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are dependent o...

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Bibliographic Details
Main Authors: Thomas Schmitt, Christoph Hudemann, Sina Moztarzadeh, Michael Hertl, Ritva Tikkanen, Jens Waschke
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
pemphigus
autoimmune disease
skin
epidermis
desmosomes
adhesion
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163066/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163066/full

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