Icariin attenuates the calcification of vascular smooth muscle cells through ERα – p38MAPK pathway

Icariin attenuates the calcification of vascular smooth muscle cells through ERα – p38MAPK pathway

Abstract Objective To investigate the relationship between icariin and the osteoblastic differentiation of vascular smooth muscle cells (VSMCs) and the signal pathway involved. Methods We applied a universally accepted calcification model of VSMCs induced by β glycerophosphate. Then the VSMCs calcif...

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Bibliographic Details
Main Authors: Jieyu He, Yanjiao Wang, Junkun Zhan, Shuang Li, Yuqing Ni, Wu Huang, Limin Long, Pan Tan, Yi Wang, Youshuo Liu
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Aging Medicine
Subjects:
estrogen receptor
icariin
mitogen‐activated protein kinase
vascular calcification
vascular smooth muscle cells
Online Access:https://doi.org/10.1002/agm2.12267

Internet

https://doi.org/10.1002/agm2.12267

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