Use of High-Frequency In-Home Monitoring Data May Reduce Sample Sizes Needed in Clinical Trials.

Trials in Alzheimer's disease are increasingly focusing on prevention in asymptomatic individuals. This poses a challenge in examining treatment effects since currently available approaches are often unable to detect cognitive and functional changes among asymptomatic individuals. Resultant sma...

Full description

Bibliographic Details
Main Authors: Hiroko H Dodge, Jian Zhu, Nora C Mattek, Daniel Austin, Judith Kornfeld, Jeffrey A Kaye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4574479?pdf=render