Crosstalk between Cancer Cells and Cancer-Associated Fibroblasts Mediated by TGF-β1–IGFBP7 Signaling Promotes the Progression of Infiltrative Gastric Cancer

Crosstalk between Cancer Cells and Cancer-Associated Fibroblasts Mediated by TGF-β1–IGFBP7 Signaling Promotes the Progression of Infiltrative Gastric Cancer

Patients with infiltrative-type gastric cancer (GC) (Ming’s classification) have a poor prognosis due to more metastasis and recurrence. Cancer-associated fibroblasts (CAFs) in infiltrative-type extracellular matrix (ECM) have specific characteristics compared with those of expansive types with resp...

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Bibliographic Details
Main Authors: Zhijun Hong, Wen Xie, Huiqin Zhuo, Xujin Wei, Kang Wang, Jia Cheng, Lingyun Lin, Jingjing Hou, Xin Chen, Jianchun Cai
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
gastric cancer
metastasis
Ming classification
cancer-associated fibroblast
IGFBP7
TGF-β1
Online Access:https://www.mdpi.com/2072-6694/15/15/3965

Internet

https://www.mdpi.com/2072-6694/15/15/3965

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