Chemo-Enzymatic Synthesis of Antagonists of the Myelin-associated Glycoprotein (MAG)

Ganglioside GQ1b ? is the most potent antagonist of the Myelin-associated glycoprotein (MAG) identified so far. For the efficient synthesis of the partial structure of GQ1b ? and derivatives thereof, a chemo-enzymatic strategy using the ?(2?3)-sialyltransferase ratST3Gal III (EC 2.4.99.6)...

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Bibliographic Details
Main Authors: Gan-Pan Gao, Oliver Schwardt, Tamara Visekruna, Said Rabbani, Beat Ernst
Format: Article
Language:deu
Published: Swiss Chemical Society 2004-04-01
Series:CHIMIA
Subjects:
Online Access:https://chimia.ch/chimia/article/view/3835