Prevalent levels of RSV serum neutralizing antibodies in healthy adults outside the RSV-season

Prevalent levels of RSV serum neutralizing antibodies in healthy adults outside the RSV-season

One of the main challenges in early clinical research with respiratory syncytial virus (RSV) live-attenuated vaccines (LAVs) is to assess immunogenicity in healthy adults. Healthy adults will have preexisting levels of serum neutralizing antibodies that could prematurely neutralize the LAV and under...

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Bibliographic Details
Main Authors: Johan L. Van Der Plas, Pauline Verdijk, Emilie M. J. Van Brummelen, Rienk E. Jeeninga, Meta Roestenberg, Jacobus Burggraaf, Ingrid M.C. Kamerling
Format: Article
Language:English
Published: Taylor & Francis Group 2020-06-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
respiratory syncytial virus
neutralizing antibodies
vaccines
live-attenuated
controlled human infection model
healthy volunteers
Online Access:http://dx.doi.org/10.1080/21645515.2019.1688040

Internet

http://dx.doi.org/10.1080/21645515.2019.1688040

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