Peptide-Functionalized Dendrimer Nanocarriers for Targeted Microdystrophin Gene Delivery

Peptide-Functionalized Dendrimer Nanocarriers for Targeted Microdystrophin Gene Delivery

Gene therapy is a good alternative for determined congenital disorders; however, there are numerous limitations for gene delivery in vivo including targeted cellular uptake, intracellular trafficking, and transport through the nuclear membrane. Here, a modified G5 polyamidoamine (G5 PAMAM) dendrimer...

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Bibliographic Details
Main Authors: Jessica Hersh, José Manuel Condor Capcha, Camila Iansen Irion, Guerline Lambert, Mauricio Noguera, Mohit Singh, Avinash Kaur, Emre Dikici, Joaquín J. Jiménez, Lina A. Shehadeh, Sylvia Daunert, Sapna K. Deo
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
nanocarriers
gene delivery
targeted delivery
functional peptides
muscular dystrophy
Online Access:https://www.mdpi.com/1999-4923/13/12/2159

Internet

https://www.mdpi.com/1999-4923/13/12/2159

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