Transferability of the PRS estimates for height and BMI obtained from the European ethnic groups to the Western Russian populations

Transferability of the PRS estimates for height and BMI obtained from the European ethnic groups to the Western Russian populations

Genetic data plays an increasingly important role in modern medicine. Decrease in the cost of sequencing with subsequent increase in imputation accuracy, and the accumulation of large amounts of high-quality genetic data enable the creation of polygenic risk scores (PRSs) to perform genotype–phenoty...

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Bibliographic Details
Main Authors: E. A. Albert, O. A. Kondratieva, E. E. Baranova, O. V. Sagaydak, M. S. Belenikin, G. Y. Zobkova, E. S. Kuznetsova, A. A. Deviatkin, A. A. Zhurov, E. A. Karpulevich, P. Y. Volchkov, M. V. Vorontsova
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
PRS
GWAS summary statistic
population structure
BMI
height
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1086709/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1086709/full

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