Tyrosine kinase inhibitors targeting vascular endothelial growth factor and the risk of aortic dissection—A pharmacovigilance analysis

Tyrosine kinase inhibitors targeting vascular endothelial growth factor and the risk of aortic dissection—A pharmacovigilance analysis

Abstract There are concerns by the United States Food and Drug Administration (FDA) regarding a potential link between tyrosine kinase inhibitors targeting vascular endothelial growth factor (VEGF‐TKIs) and the risk of aortic dissection. Elevation of blood pressure induced by VEGF‐TKIs has been disc...

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Bibliographic Details
Main Authors: Michael Dörks, Kathrin Jobski, Stefan Herget‐Rosenthal, Falk Hoffmann, Antonios Douros
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Pharmacology Research & Perspectives
Subjects:
cardiovascular toxicity
drug safety
tyrosine kinase inhibitors
Online Access:https://doi.org/10.1002/prp2.707

Internet

https://doi.org/10.1002/prp2.707

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