Extended infusion of β-lactams significantly reduces mortality and enhances microbiological eradication in paediatric patients: a systematic review and meta-analysisResearch in context

Extended infusion of β-lactams significantly reduces mortality and enhances microbiological eradication in paediatric patients: a systematic review and meta-analysisResearch in context

Summary: Background: Paediatric patients are often exposed to subtherapeutic levels or treatment failure of β-lactams, and prolonged infusion may be beneficial. We aimed to investigate the efficacy and safety of extended infusion (EI; defined as ≥3 h) or continuous infusion vs. short, intermittent...

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Bibliographic Details
Main Authors: Kinga Anna Budai, Ágnes Eszter Tímár, Mahmoud Obeidat, Vanda Máté, Rita Nagy, Andrea Harnos, Szilvia Kiss-Dala, Péter Hegyi, Miklós Garami, Balázs Hankó, Csaba Lódi
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:EClinicalMedicine
Subjects:
Beta-lactam
Extended infusion
Continuous infusion
Paediatric patients
Mortality
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537023004704

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http://www.sciencedirect.com/science/article/pii/S2589537023004704

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