Identifying cellular markers of focal cortical dysplasia type II with cell-type deconvolution and single-cell signatures

Abstract Focal cortical dysplasia (FCD) is a brain malformation that causes medically refractory epilepsy. FCD is classified into three categories based on structural and cellular abnormalities, with FCD type II being the most common and characterized by disrupted organization of the cortex and abno...

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Main Authors: Isabella C. Galvão, Ludmyla Kandratavicius, Lauana A. Messias, Maria C. P. Athié, Guilherme R. Assis-Mendonça, Marina K. M. Alvim, Enrico Ghizoni, Helder Tedeschi, Clarissa L. Yasuda, Fernando Cendes, André S. Vieira, Fabio Rogerio, Iscia Lopes-Cendes, Diogo F. T. Veiga
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40240-3