Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia

Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia

Loneliness and social isolation (LNL-ISO) are associated with schizophrenia. Here the authors demonstrate the role of shared heritability, bidirectional causal relationships and significant differences by sex, illustrating the genomic footprint of social isolation on schizophrenia.

Bibliographic Details
Main Authors: Álvaro Andreu-Bernabeu, Covadonga M. Díaz-Caneja, Javier Costas, Lucía De Hoyos, Carol Stella, Xaquín Gurriarán, Clara Alloza, Lourdes Fañanás, Julio Bobes, Ana González-Pinto, Benedicto Crespo-Facorro, Lourdes Martorell, Elisabet Vilella, Gerard Muntané, Juan Nacher, María Dolores Molto, Eduardo Jesús Aguilar, Mara Parellada, Celso Arango, Javier González-Peñas
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27598-6

Internet

https://doi.org/10.1038/s41467-021-27598-6

Similar Items