Dissecting the Regulation of Arachidonic Acid Metabolites by Uncaria rhynchophylla (Miq). Miq. in Spontaneously Hypertensive Rats and the Predictive Target sEH in the Anti-Hypertensive Effect Based on Metabolomics and Molecular Docking

Dissecting the Regulation of Arachidonic Acid Metabolites by Uncaria rhynchophylla (Miq). Miq. in Spontaneously Hypertensive Rats and the Predictive Target sEH in the Anti-Hypertensive Effect Based on Metabolomics and Molecular Docking

Uncariarhynchophylla (Miq). Miq. (UR), as a traditional Chinese medicine, was employed in treating hypertension as a safe and effective therapy. The pharmacological properties of UR have characteristics of multiple biological targets and multiple functional pathways. Hypertension is related to impai...

Full description

Bibliographic Details
Main Authors: Lei Gao, Xinqin Kong, Wenyong Wu, Zijin Feng, Haijuan Zhi, Zijia Zhang, Huali Long, Min Lei, Jinjun Hou, Wanying Wu, De-an Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
Uncaria
anti-hypertensive
arachidonic acid metabolites
sEH = soluble epoxide hydrolase
EETS
metabolomics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.909631/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.909631/full

Similar Items