Development of HEK-293 Cell Lines Constitutively Expressing Flaviviral Antigens for Use in Diagnostics

Development of HEK-293 Cell Lines Constitutively Expressing Flaviviral Antigens for Use in Diagnostics

ABSTRACT Flaviviruses are important human pathogens worldwide. Diagnostic testing for these viruses is difficult because many of the pathogens require specialized biocontainment. To address this issue, we generated 39 virus-like particle (VLP)- and nonstructural protein 1 (NS1)-secreting stable cell...

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Bibliographic Details
Main Authors: Jordan A. Powers, Benjamin Skinner, Brent S. Davis, Brad J. Biggerstaff, Lucy Robb, Elizabeth Gordon, William M. de Souza, Marcilio Jorge Fumagalli, Amanda E. Calvert, Gwong-Jen Chang
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
arbovirus
diagnostics
flavivirus
recombinant protein production
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00592-22

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https://journals.asm.org/doi/10.1128/spectrum.00592-22

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