A Role for RAGE in DNA Double Strand Breaks (DSBs) Detected in Pathological Placentas and Trophoblast Cells

A Role for RAGE in DNA Double Strand Breaks (DSBs) Detected in Pathological Placentas and Trophoblast Cells

Impaired DNA damage responses are associated with several diseases, including pregnancy complications. Recent research identified an ATM-kinase dependent function for the nuclear isoform of the receptor for advanced glycation end-products (RAGE) during double strand break (DSB)-repair. RAGE contribu...

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Bibliographic Details
Main Authors: Kary Y.F. Tsai, Benton Tullis, Katrina L. Breithaupt, Rylan Fowers, Nelson Jones, Samuel Grajeda, Paul R. Reynolds, Juan A. Arroyo
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
DSB
RAGE
placenta
γ-H2AX
pATM
MRE11
Online Access:https://www.mdpi.com/2073-4409/10/4/857

Internet

https://www.mdpi.com/2073-4409/10/4/857

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