Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NF-κB activation via disrupting multiple-site ubiquitination of NEMO

Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NF-κB activation via disrupting multiple-site ubiquitination of NEMO

Abstract Background Bladder cancer (BLCA) is a malignancy that frequently metastasizes and leads to poor patient prognosis. It is essential to understand the molecular mechanisms underlying the progression and metastasis of BLCA and identify potential biomarkers. Methods The expression of peptidase...

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Bibliographic Details
Main Authors: Xiangqin Kuang, Zhuojun Zhang, Difeng Li, Wenhao Bao, Jinyuan Pan, Ping Zhou, Han Chen, Zhiqing Gao, Xiaoyi Xie, Chunxiao Yang, Ge Zhu, Zhongqiu Zhou, Ruiming Tang, Zhengfu Feng, Lihuan Zhou, Xiaoli Feng, Lan Wang, Jianan Yang, Lili Jiang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Cellular & Molecular Biology Letters
Subjects:
Bladder cancer
PI16
NF-κB
Ubiquitination
Online Access:https://doi.org/10.1186/s11658-023-00465-6

Internet

https://doi.org/10.1186/s11658-023-00465-6

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