δ-opioid receptor and somatostatin receptor-4 heterodimerization: possible implications in modulation of pain associated signaling.
Pain relief is the principal action of opioids. Somatostatin (SST), a growth hormone inhibitory peptide is also known to alleviate pain even in cases when opioids fail. Recent studies have shown that mice are prone to sustained pain and devoid of analgesic effect in the absence of somatostatin recep...
Автори: | , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
Public Library of Science (PLoS)
2014-01-01
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Серія: | PLoS ONE |
Онлайн доступ: | http://europepmc.org/articles/PMC3885706?pdf=render |