δ-opioid receptor and somatostatin receptor-4 heterodimerization: possible implications in modulation of pain associated signaling.

Pain relief is the principal action of opioids. Somatostatin (SST), a growth hormone inhibitory peptide is also known to alleviate pain even in cases when opioids fail. Recent studies have shown that mice are prone to sustained pain and devoid of analgesic effect in the absence of somatostatin recep...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Rishi K Somvanshi, Ujendra Kumar
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2014-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3885706?pdf=render

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