Epithelial–Mesenchymal Transition Signaling and Prostate Cancer Stem Cells: Emerging Biomarkers and Opportunities for Precision Therapeutics

Epithelial–Mesenchymal Transition Signaling and Prostate Cancer Stem Cells: Emerging Biomarkers and Opportunities for Precision Therapeutics

Prostate cancers may reactivate a latent embryonic program called the epithelial–mesenchymal transition (EMT) during the development of metastatic disease. Through EMT, tumors can develop a mesenchymal phenotype similar to cancer stem cell traits that contributes to metastasis and variation in thera...

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Bibliographic Details
Main Authors: Luiz Paulo Chaves, Camila Morais Melo, Fabiano Pinto Saggioro, Rodolfo Borges dos Reis, Jeremy Andrew Squire
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Genes
Subjects:
castrate-resistant prostate cancer
immunotherapy
immune evasion
tumor microenvironment
oncogenes
tumor suppressor genes
Online Access:https://www.mdpi.com/2073-4425/12/12/1900

Internet

https://www.mdpi.com/2073-4425/12/12/1900

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