The role of HIF-1α in hypoxic metabolic reprogramming in osteoarthritis

The joint dysfunction caused by osteoarthritis (OA) is increasingly becoming a major challenge in global healthcare, and there is currently no effective strategy to prevent the progression of OA. Therefore, better elucidating the relevant mechanisms of OA occurrence and development will provide theo...

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Bibliographic Details
Main Authors: Jie Zhang, Peng Gao, Wei-Rong Chang, Jia-Yi Song, Fang-Yu An, Yu-Jie Wang, Zhi-Pan Xiao, Hua Jin, Xu-Hui Zhang, Chun-Lu Yan
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Pharmacological Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S104366182500074X