Gold nanoparticle based double-labeling of melanoma extracellular vesicles to determine the specificity of uptake by cells and preferential accumulation in small metastatic lung tumors

Gold nanoparticle based double-labeling of melanoma extracellular vesicles to determine the specificity of uptake by cells and preferential accumulation in small metastatic lung tumors

Abstract Background Extracellular vesicles (EVs) have shown great potential for targeted therapy, as they have a natural ability to pass through biological barriers and, depending on their origin, can preferentially accumulate at defined sites, including tumors. Analyzing the potential of EVs to tar...

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Bibliographic Details
Main Authors: Pablo Lara, Sujey Palma-Florez, Edison Salas-Huenuleo, Iva Polakovicova, Simón Guerrero, Lorena Lobos-Gonzalez, America Campos, Luis Muñoz, Carla Jorquera-Cordero, Manuel Varas-Godoy, Jorge Cancino, Eloísa Arias, Jaime Villegas, Luis J. Cruz, Fernando Albericio, Eyleen Araya, Alejandro H. Corvalan, Andrew F. G. Quest, Marcelo J. Kogan
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Nanobiotechnology
Subjects:
Extracellular vesicles
Exosomes
Gold nanoparticles
Metastasis
Tracking
Targeting
Online Access:https://doi.org/10.1186/s12951-020-0573-0

Internet

https://doi.org/10.1186/s12951-020-0573-0

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