Age‐Associated Changes in Endothelial Transcriptome and Epigenetic Landscapes Correlate With Elevated Risk of Cerebral Microbleeds

Background Stroke is a leading global cause of human death and disability, with advanced aging associated with elevated incidences of stroke. Despite high mortality and morbidity of stroke, the mechanisms leading to blood‐brain barrier dysfunction and development of stroke with age are poorly unders...

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Bibliographic Details
Main Authors: Kshitij Mohan, Gilles Gasparoni, Abdulrahman Salhab, Michael M. Orlich, Robert Geffers, Steve Hoffmann, Ralf H. Adams, Jörn Walter, Alfred Nordheim
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.031044