Niacin analogue, 6-Aminonicotinamide, a novel inhibitor of hepatitis B virus replication and HBsAg production

Background: Hepatitis B surface antigen (HBsAg) is one of the important clinical indexes for hepatitis B virus (HBV) infection diagnosis and sustained seroconversion of HBsAg is an indicator for functional cure. However, the level of HBsAg could not be reduced by interferons and nucleoside analogs e...

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Main Authors: Fang Ren, Xiao Yang, Zhong-Wen Hu, Vincent Kam Wai Wong, Hong-Yan Xu, Ji-Hua Ren, Shan Zhong, Xiao-Jiong Jia, Hui Jiang, Jie-Li Hu, Xue-Fei Cai, Wen-Lu Zhang, Fang-Long Yao, Hai-Bo Yu, Sheng-Tao Cheng, Hong-Zhong Zhou, Ai-Long Huang, Betty Yuen Kwan Law, Juan Chen
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419306863