DNA quality evaluation of formalin-fixed paraffin-embedded heart tissue for DNA methylation array analysis

Abstract Archived formalin-fixed and paraffin-embedded (FFPE) heart tissue from autopsied individuals represents an important resource for investigating the DNA methylation of heart tissue of deceased individuals. The DNA quality of FFPE tissue from autopsies may be decreased, affecting the DNA meth...

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Bibliographic Details
Main Authors: Mikkel E. Dupont, Steffan N. Christiansen, Stine B. Jacobsen, Marie-Louise Kampmann, Kristine B. Olsen, Jacob Tfelt-Hansen, Jytte Banner, Niels Morling, Jeppe D. Andersen
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29120-y