YY1: a key regulator inhibits gastric cancer ferroptosis and mediating apatinib-resistance
Abstract Objective Gastric cancer (GC) stands as a prevalent and deadly global malignancy. Despite its role as a preoperative neoadjuvant therapy, Apatinib’s effectiveness is curtailed among GC patients exhibiting elevated YY1 expression. YY1’s connection to adverse prognosis, drug resistance, and G...
Main Authors: | Zi-Han Geng, Jun-Xian Du, Yue-Da Chen, Pei-Yao Fu, Ping-Hong Zhou, Wen-Zheng Qin, Yi-Hong Luo |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
|
Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-024-03262-z |
Similar Items
-
Expression of p53 as a biomarker in determining response to apatinib for advanced gastric cancer
by: Zhiyuan Qiu, et al.
Published: (2023-08-01) -
SIRT1 is transcriptionally repressed by YY1 and suppresses ferroptosis in rheumatoid arthritis
by: Yuwei Zhan, et al.
Published: (2023-03-01) -
Apatinib Promotes Ferroptosis in Colorectal Cancer Cells by Targeting ELOVL6/ACSL4 Signaling
by: Tian X, et al.
Published: (2021-02-01) -
Apatinib enhances chemosensitivity of gastric cancer to paclitaxel and 5-fluorouracil
by: Xu Z, et al.
Published: (2019-05-01) -
Effectiveness and safety of low‐dose apatinib in advanced gastric cancer: A real‐world study
by: Yingying Du, et al.
Published: (2020-07-01)