YY1: a key regulator inhibits gastric cancer ferroptosis and mediating apatinib-resistance

Abstract Objective Gastric cancer (GC) stands as a prevalent and deadly global malignancy. Despite its role as a preoperative neoadjuvant therapy, Apatinib’s effectiveness is curtailed among GC patients exhibiting elevated YY1 expression. YY1’s connection to adverse prognosis, drug resistance, and G...

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Bibliographic Details
Main Authors: Zi-Han Geng, Jun-Xian Du, Yue-Da Chen, Pei-Yao Fu, Ping-Hong Zhou, Wen-Zheng Qin, Yi-Hong Luo
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-024-03262-z