Transcriptional effects of inhibiting epidermal growth factor receptor in keratinocytes

Background: Epidermal growth factor receptor (EGFR) activation is important in human epithelial malignancies, including cutaneous squamous cell carcinoma, lung, colon, pancreatic, and other cancers. Therapies targeting EGFR are currently used to treat such cancers, but one significant drawback to EG...

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Bibliographic Details
Main Authors: Alix Gazel, Miroslav Blumenberg
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-09-01
Series:Dermatologica Sinica
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1027811712001048