Tenofovir-tethered gold nanoparticles as a novel multifunctional long-acting anti-HIV therapy to overcome deficient drug delivery-: an in vivo proof of concept

Tenofovir-tethered gold nanoparticles as a novel multifunctional long-acting anti-HIV therapy to overcome deficient drug delivery-: an in vivo proof of concept

Abstract Background The adoption of Antiretroviral Therapy (ART) substantially extends the life expectancy and quality of HIV-infected patients. Yet, eliminating the latent reservoirs of HIV to achieve a cure remains an unmet need. The advent of nanomedicine has revolutionized the treatment of HIV/A...

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Bibliographic Details
Main Authors: Leila Fotooh Abadi, Pramod Kumar, Kishore Paknikar, Virendra Gajbhiye, Smita Kulkarni
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Nanobiotechnology
Subjects:
NanoART
Long-acting antiretroviral
Genotoxicology
HIV reservoirs
Preclinical
Biodistribution
Online Access:https://doi.org/10.1186/s12951-022-01750-w

Internet

https://doi.org/10.1186/s12951-022-01750-w

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