Phenotypic and genetic characterization of daptomycin non-susceptible Staphylococcus aureus strains selected by adaptive laboratory evolution

BackgroundDaptomycin non-susceptible Staphylococcus aureus (DNS) strains pose a serious clinical threat, yet their characteristics remain poorly understood.MethodsDNS derivatives were generated by exposing S. aureus strains to subinhibitory concentrations of daptomycin. Competition experiment and gr...

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Bibliographic Details
Main Authors: Yanlei Xu, Yanghua Xiao, Huilin Zhao, Bingjie Wang, Jingyi Yu, Yongpeng Shang, Ying Zhou, Xiaocui Wu, Yinjuan Guo, Fangyou Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1453233/full