Tailorable Hydrogel Improves Retention and Cardioprotection of Intramyocardial Transplanted Mesenchymal Stem Cells for the Treatment of Acute Myocardial Infarction in Mice

Tailorable Hydrogel Improves Retention and Cardioprotection of Intramyocardial Transplanted Mesenchymal Stem Cells for the Treatment of Acute Myocardial Infarction in Mice

Background Poor engraftment of intramyocardial stem cells limits their therapeutic efficiency against myocardial infarction (MI)‐induced cardiac injury. Transglutaminase cross‐linked Gelatin (Col‐Tgel) is a tailorable collagen‐based hydrogel that is becoming an excellent biomaterial scaffold for cel...

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Bibliographic Details
Main Authors: Youhu Chen, Congye Li, Chengxiang Li, Jiangwei Chen, Yan Li, Huaning Xie, Chen Lin, Miaomiao Fan, Yongzhen Guo, Erhe Gao, Wenjun Yan, Ling Tao
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
3D culture
mesenchymal stem cells
myocardial infarction
transglutaminase cross‐linked gelatin
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.013784

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.119.013784

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