Head-to-head comparison of relative cerebral blood flow derived from dynamic [18F]florbetapir and [18F]flortaucipir PET in subjects with subjective cognitive decline

Head-to-head comparison of relative cerebral blood flow derived from dynamic [18F]florbetapir and [18F]flortaucipir PET in subjects with subjective cognitive decline

Abstract Background Dynamic PET imaging studies provide accurate estimates of specific binding, but also measure the relative tracer delivery (R1), which is a proxy for relative cerebral blood flow (rCBF). Recently, studies suggested that R1 obtained from different tracers could be used interchangea...

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Bibliographic Details
Main Authors: Hayel Tuncel, Denise Visser, Tessa Timmers, Emma E. Wolters, Rik Ossenkoppele, Wiesje M. van der Flier, Bart N. M. van Berckel, Ronald Boellaard, Sandeep S. V. Golla
Format: Article
Language:English
Published: SpringerOpen 2023-10-01
Series:EJNMMI Research
Subjects:
PET
Relative cerebral blood flow
[18F]florbetapir
[18F]flortaucipir
SCD
Online Access:https://doi.org/10.1186/s13550-023-01041-x

Internet

https://doi.org/10.1186/s13550-023-01041-x

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