Inhibition of Galectins and the P2X7 Purinergic Receptor as a Therapeutic Approach in the Neurovascular Inflammation of Diabetic Retinopathy

Inhibition of Galectins and the P2X7 Purinergic Receptor as a Therapeutic Approach in the Neurovascular Inflammation of Diabetic Retinopathy

Diabetic retinopathy (DR) is the most frequent microvascular retinal complication of diabetic patients, contributing to loss of vision. Recently, retinal neuroinflammation and neurodegeneration have emerged as key players in DR progression, and therefore, this review examines the neuroinflammatory m...

Full description

Bibliographic Details
Main Authors: Caterina Claudia Lepre, Marina Russo, Maria Consiglia Trotta, Francesco Petrillo, Fabiana Anna D’Agostino, Gennaro Gaudino, Giovanbattista D’Amico, Maria Rosaria Campitiello, Erminia Crisci, Maddalena Nicoletti, Carlo Gesualdo, Francesca Simonelli, Michele D’Amico, Anca Hermenean, Settimio Rossi
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
diabetic retinopathy
neuroinflammation
ROS
ER stress
NLRP3 inflammasome
galectins
Online Access:https://www.mdpi.com/1422-0067/24/11/9721

Internet

https://www.mdpi.com/1422-0067/24/11/9721

Similar Items