Aldehyde dehydrogenase 2-mediated aldehyde metabolism promotes tumor immune evasion by regulating the NOD/VISTA axis

Background Aldehyde dehydrogenase 2 (ALDH2) is a crucial enzyme involved in endogenous aldehyde detoxification and has been implicated in tumor progression. However, its role in tumor immune evasion remains unclear.Methods Here, we analyzed the relationship between ALDH2 expression and antitumor imm...

Full description

Bibliographic Details
Main Authors: Qin Li, Jing Huang, Xiaoyi Wang, Huiying Fang, Guosheng Ren, Xiaoyu Wang, Yuru Chen, Jiazheng Sun, Jiazhou Liu, Yuxian Wei, Huimin Du, Hongzhong Li
Format: Article
Language:English
Published: BMJ Publishing Group 2023-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/12/e007487.full