Inhibition of spinal ferroptosis-like cell death alleviates hyperalgesia and spontaneous pain in a mouse model of bone cancer pain

Bone cancer pain (BCP) impairs patients’ quality of life. However, the underlying mechanisms are still unclear. This study investigated the role of spinal interneuron death using a pharmacological inhibitor of ferroptosis in a mouse model of BCP. Lewis lung carcinoma cells were inoculated into the f...

Full description

Bibliographic Details
Main Authors: Zhuofeng Ding, Xiaoshen Liang, Jian Wang, Zongbin Song, Qulian Guo, Michael K.E. Schäfer, Changsheng Huang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723001015