Improving the statistical detection of regulated genes from microarray data using intensity-based variance estimation

<p>Abstract</p> <p>Background</p> <p>Gene microarray technology provides the ability to study the regulation of thousands of genes simultaneously, but its potential is limited without an estimate of the statistical significance of the observed changes in gene expression...

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Bibliographic Details
Main Authors: Natarajan Sripriya, Comander Jason, Gimbrone Michael A, García-Cardeña Guillermo
Format: Article
Language:English
Published: BMC 2004-02-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/5/17