Prenatal stress enhances excitatory synaptic transmission and impairs long-term potentiation in the frontal cortex of adult offspring rats.

The effects of prenatal stress procedure were investigated in 3 months old male rats. Prenatally stressed rats showed depressive-like behavior in the forced swim test, including increased immobility, decreased mobility and decreased climbing. In ex vivo frontal cortex slices originating from prenata...

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Bibliographic Details
Main Authors: Joanna Sowa, Bartosz Bobula, Katarzyna Glombik, Joanna Slusarczyk, Agnieszka Basta-Kaim, Grzegorz Hess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4352064?pdf=render