Strain-level detection of Fusobacterium nucleatum in colorectal cancer specimens by targeting the CRISPR–Cas region

Strain-level detection of Fusobacterium nucleatum in colorectal cancer specimens by targeting the CRISPR–Cas region

ABSTRACT Fusobacterium nucleatum is associated with colorectal cancer (CRC), and identical F. nucleatum strains seemed to be detected in 75% of patients who exhibited the presence of F. nucleatum in both CRC and saliva samples in our previous study; however, the validation of strain identity and the...

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Bibliographic Details
Main Authors: Yumi Shimomura, Yutaka Sugi, Aiko Kume, Wataru Tanaka, Tsutomu Yoshihara, Tetsuya Matsuura, Yasuhiko Komiya, Yusuke Ogata, Wataru Suda, Masahira Hattori, Takuma Higurashi, Atsushi Nakajima, Mitsuharu Matsumoto
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
Fusobacterium nucleatum
colorectal cancer
CRISPR–Cas system
polymerase chain reaction
strain level
saliva
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05123-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05123-22

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