Impact of treatment adherence on efficacy of dolutegravir plus lamivudine and dolutegravir plus tenofovir disoproxil fumarate/emtricitabine: pooled analysis of the GEMINI-1 and GEMINI-2 clinical studies

Impact of treatment adherence on efficacy of dolutegravir plus lamivudine and dolutegravir plus tenofovir disoproxil fumarate/emtricitabine: pooled analysis of the GEMINI-1 and GEMINI-2 clinical studies

Background: GEMINI-1 and GEMINI-2 (ClinicalTrials.gov, NCT02831673 and NCT02831764, respectively) are double-blind, multicenter, phase III studies that demonstrated the non-inferiority of once-daily dolutegravir + lamivudine to dolutegravir + tenofovir disoproxil fumarate/emtricitabine in achieving...

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Bibliographic Details
Main Authors: Mounir Ait-Khaled, Juan Sierra Madero, Vicente Estrada, Roberto Gulminetti, Debbie Hagins, Hung-Chin Tsai, Choy Man, Jörg Sievers, Richard Grove, Andrew Zolopa, Brian Wynne, Jean van Wyk
Format: Article
Language:English
Published: Taylor & Francis Group 2021-12-01
Series:HIV Research & Clinical Practice
Subjects:
2-drug regimen
integrase strand transfer inhibitor
nucleoside reverse transcriptase inhibitor
antiretroviral therapy
virologic suppression
Online Access:http://dx.doi.org/10.1080/25787489.2021.2016303

Internet

http://dx.doi.org/10.1080/25787489.2021.2016303

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