PARP Inhibitors in Advanced Prostate Cancer in Tumors with DNA Damage Signatures

Since 2010, significant progress has been made in the treatment of metastatic castrate resistant prostate cancer (mCRPC). While these advancements have improved survival, mCRPC remains a lethal disease, with a precision medicine framework that is lagging behind compared to other cancers. Poly (ADP-r...

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Bibliographic Details
Main Authors: Ciara S. McNevin, Karen Cadoo, Anne-Marie Baird, Stephen P. Finn, Ray McDermott
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/19/4751