The central blockade of the dopamine DR4 receptor decreases sucrose consumption by modifying the microstructure of drinking behavior in male rats

Sugar solutions promote hedonic feeding and increase the risk of obesity and binge-type behavior. In rodents, ingestion of sugar solutions enhances dopamine release to mesolimbic regions, suggesting changes in hedonic intake and brain reward processes. Moreover, dopaminergic D2R/D3R receptors contri...

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Bibliographic Details
Main Authors: Verónica E. López-Alonso, Samantha Hernández-Correa, Carolina Escobar, Rodrigo E. Escartín-Pérez, Juan M. Mancilla-Díaz, Daniel Díaz-Urbina
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:IBRO Neuroscience Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242123000118