SENP3 Aggravates Renal Tubular Epithelial Cell Apoptosis in Lipopolysaccharide-Induced Acute Kidney Injury via deSUMOylation of Drp1
Background: Sepsis causes acute kidney injury (AKI) in critically ill patients, although the mechanisms underlying the pathophysiology are not fully understood. SUMO-specific proteases 3 (SENP3), a member of the deSUMOylating enzyme family, is known as a redox sensor and could regulate multiple cell...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Karger Publishers
2022-06-01
|
Series: | Kidney Diseases |
Subjects: | |
Online Access: | https://beta.karger.com/Article/FullText/525308 |