SENP3 Aggravates Renal Tubular Epithelial Cell Apoptosis in Lipopolysaccharide-Induced Acute Kidney Injury via deSUMOylation of Drp1

Background: Sepsis causes acute kidney injury (AKI) in critically ill patients, although the mechanisms underlying the pathophysiology are not fully understood. SUMO-specific proteases 3 (SENP3), a member of the deSUMOylating enzyme family, is known as a redox sensor and could regulate multiple cell...

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Bibliographic Details
Main Authors: Lirui Wang, Jiangtao Li, Chen Yu
Format: Article
Language:English
Published: Karger Publishers 2022-06-01
Series:Kidney Diseases
Subjects:
Online Access:https://beta.karger.com/Article/FullText/525308