Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR

Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR

Background: Depression is a highly prevalent disorder that is one of the leading causes of disability worldwide. Despite an unknown aetiology, evidence suggests that the innate and adaptive immune systems play a significant role in the development and maintenance of major depressive disorder (MDD)....

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Main Authors: Wanda Nowak, Leandro Nicolás Grendas, Liliana María Sanmarco, Ivana Gisele Estecho, Ángeles Romina Arena, Natalia Eberhardt, Demián Emanuel Rodante, María Pilar Aoki, Federico Manuel Daray, Eugenio Antonio Carrera Silva, Andrea Emilse Errasti
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419307406

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http://www.sciencedirect.com/science/article/pii/S2352396419307406

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