Peripheral Fragile X messenger ribonucleoprotein is required for the timely closure of a critical period for neuronal susceptibility in the ventral cochlear nucleus

Peripheral Fragile X messenger ribonucleoprotein is required for the timely closure of a critical period for neuronal susceptibility in the ventral cochlear nucleus

Alterations in neuronal plasticity and critical periods are common across neurodevelopmental diseases, including Fragile X syndrome (FXS), the leading single-gene cause of autism. Characterized with sensory dysfunction, FXS is the result of gene silencing of Fragile X messenger ribonucleoprotein 1 (...

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Bibliographic Details
Main Authors: Xiaoyan Yu, Yuan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Fragile X syndrome
critical period
sensory organ
afferent influence
hearing onset
brain development
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1186630/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1186630/full

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