Patient-derived tumor models: a more suitable tool for pre-clinical studies in colorectal cancer

Abstract Colorectal cancer (CRC), despite the advances in screening and surveillance, remains the second most common cause of cancer death worldwide. The biological inadequacy of pre-clinical models to fully recapitulate the multifactorial etiology and the complexity of tumor microenvironment and hu...

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Bibliographic Details
Main Authors: Giulia Rizzo, Andrea Bertotti, Simonetta Maria Leto, Stefania Vetrano
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-021-01970-2