Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway

Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway

Abstract Background One of the most challenging aspects of colon cancer (CC) prognosis and treatment is liver-tropic metastasis. Astragalus mongholicus Bunge—Curcuma aromatica Salisb. (AC) is a typical medication combination for the therapy of many malignancies. Our previous studies found that AC in...

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Bibliographic Details
Main Authors: Fuyan Liu, Yan Liang, Ruolan Sun, Weicheng Yang, Zhongqing Liang, Junfei Gu, Fan Zhao, Decai Tang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Chinese Medicine
Subjects:
Liver metastasis of Colon cancer
Traditional Chinese Medicine
CXCL8
PI3K/AKT signaling pathway
EMT
Online Access:https://doi.org/10.1186/s13020-022-00641-4

Internet

https://doi.org/10.1186/s13020-022-00641-4

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